Calgary police are in the southeast community of Southview, where car slammed into home, and witnesses reported hearing gunshots shortly afterwards.
Just before midnight, police were called to a home along 26 Street S.E.
When they got to the scene, the found the vehicle and damaged home.
One man was inside the car, suffering from a gunshot wound. Another man was found walking away from the car, also suffering from a gunshot wound.
No one inside the home was hurt.
The two men were taken to hospital in serious, non-life-threatening condition.
Neither suspect is cooperating with police.